![]() ![]() Evidence-Based Complementary and Alternative Medicine. "Efficacy and Safety of Pomegranate Medicinal Products for Cancer". ^ Vlachojannis, Christian Zimmerman, Benno F Chrubasik-Hausmann, Sigmun (2015)."Evidence for the effectiveness of pomegranate supplementation for blood pressure management is weak: A systematic review of randomized clinical trials". ^ Gbinigie, OA Onakpoya, IJ Spencer, EA (Oct 2017). ![]() District Court has been pending since May 23, 2012. In May 2012, after a hearing, the administrative law judge issued an opinion upholding certain false advertising allegations in the FTC's complaint-based on implied as opposed to express claims-and finding for POM Wonderful on other points. As of September 2010, the company and its principals were the subjects of a false advertising complaint by the Federal Trade Commission (FTC). The health benefits of pomegranate juice were promoted by POM Wonderful, a pomegranate products manufacturer. Doctors suspected competitive inhibition of P450 enzymes in the liver by the pomegranate juice (much like grapefruit juice). After three weeks of drinking 200ml pomegranate juice twice a week, he presented urgently with thigh pain and an elevated serum creatine kinase level indicating rhabdomyolysis. A 48-year-old man with possible underlying myopathy was uneventfully treated with ezetimibe 10 mg/day and rosuvastatin 5 mg every other day for 17 months. Any potential benefits also need to be balanced against its high caloric content derived from its natural sugars. Various primary studies have been conducted into possible health benefits derived from drinking pomegranate juice, but there is no strong evidence to suggest any effect in blood pressure management, cancer treatment, glucose and insulin management, or heart disease. ![]()
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